AO Research Institute Davos’ purpose

To further the AO's mission, ARI advances innovation in orthopedics through translational research and development.

Orthopedics concerns musculoskeletal, spine, and craniomaxillofacial trauma, degenerative musculoskeletal diseases, infections, and congenital disorders.

AO Research Institute Davos goals

Overall goals

  • Contribute high-quality applied preclinical research and development (exploratory and translational) focused on clinical solutions and applications.
  • Investigate and improve the performance of materials, biologics, and devices for surgical procedures and treatments.
  • Foster a close relationship with the AO network, academic societies, and universities.
  • Provide a supportive, inclusive and diverse research environment and mentorship for our employees, scientists, and the AO network.

ARI goals, 2023-25

  • Valorize AO Fracture Monitor together with AO Innovation Translation Center (AO ITC).
  • Implement the specific-pathogen-free sheep flock in studies.
  • Valorize the biphasic plate together with AO ITC.
  • Strengthen and advance research activities in patient diagnostics and personalized medicine.
  • Develop training technologies to support education within the AO network.
  • Continue developing 3D (bio)printing and SIM technologies.

ARI principles

  • Maintain world-class research standing and nurture in-house talents for long-term innovation.
  • Support the AO network with cutting-edge research and development for clinical problems.
  • Continue developing ARI technology portfolio. Translate and valorize ARI innovations together with the AO ITC's Technology Transfer team.
  • Maintain our world-class certifications (ISO, AAALAC, GLP).
  • Engage with scientific networks and consortia: global (eg, ORS, TERMIS, ICORS) and European societies (eg, DKOU, ECLAM, ESB-Biomaterials, ESB-Biomechanics, EORS, TERMIS-EU).


AO Research Institute Davos projects are applied preclinical research or applied preclinical development projects focused towards clinical applications. Definitions (within the applied research):

  • Exploratory applied preclinical research is fundamental research, to solve major clinical problems over an extended timeframe (over ten years).
  • Translational applied preclinical research aims at developing a clinical applicable result in around five years and builds upon the fundamental applied preclinical research. This research is usually not possible without the previous fundamental applied preclinical research.

Research programs

Regenerative Orthopaedics

The Regenerative Orthopaedics program is a multidisciplinary group taking an holistic approach to regenerative medicine for the repair of traumatic injuries of the musculoskeletal system.

Biomedical Development

The Biomedical Development program offers extensive know-how, expertise, and experience in the fields of biomechanical testing and computational analyses to advance patient care.

Preclinical Services

Preclinical Services conduct all AO Research Institute Davos in vivo studies—often in close collaboration with other focus areas.

AO Research Institute Davos history

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Contact and staff

Advisory committee

Diversity and inclusion

CRO services and resources

Publications and activity reports

Take our virtual tour

The nine videos show you a taste of the projects and areas of the AO Research Institute Davos (ARI), from our research programs and focus areas.